Compression socks have the greatest pressure at the ankle and sequentially less up the leg. They help conditions like swelling of the lower extremities, varicose veins, fatigue of the legs, blood clots, calf muscle cramps, tired, aching feet and legs, and lymphedema in the legs and feet. [1]

If you have any of the mentioned conditions, ask your doctor to prescribe compression socks.

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[1] http://www.livestrong.com/article/68749-compression-socks-work/
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