Isopropyl alcohol, or rubbing alcohol, is a powerful antiseptic that can fight odor-causing bacteria in your shoes. Simply mix some alcohol and water in a spray bottle and mist the interior of your shoes. Be sure to use an alcohol that ranges in strength from 70–99%, and let your shoes dry overnight. Come morning, any lingering odor inside of your shoes should be gone.*
When drying your shoes overnight, do not put them in a closet; leave them in an area with plenty of air circulation. Avoid getting alcohol on the outside of your shoes because it can ruin their surface.
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Photo | Ryan Hyde | Mosquito Bite Cure | Used under a Creative Commons Attribution Share-alike license